EasySep™小鼠TIL（CD45）正选试剂盒
EpiCult™ 乳腺细胞培养基
无血清、成分明确的乳腺上皮细胞培养基
EpiCult™ 是一系列无血清、成分明确的培养基，支持乳腺上皮细胞单层培养，并可用于检测乳腺集落形成单位（Ma-CFUs）或基于3D Matrigel®培养体系中的乳腺前体细胞存在。对于有兴趣培养源自乳腺癌细胞系的乳腺球或肿瘤球的研究人员，请访问我们的 页面，了解专为此目的设计和优化的、发表文献最多的商用培养基。
EpiCult™-C：培养人乳腺上皮细胞
EpiCult™-C 培养基经过优化，支持人类乳腺腔上皮细胞和肌上皮细胞的短期培养。当补充胶原酶/透明质酸酶时，也可用于人类乳腺组织的酶解分离。观看此视频了解更多信息。
Key Applications
Publications on Normal Mammary Cells
EpiCult™-B (Human)
Eirew P et al. (2008) A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med 14(12): 1384-9.
Raouf A et al. (2008) Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell 3(1): 109-18.
Stingl J et al. (2001) Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue.Breast Cancer Res Treat 67(2): 93-109.
Raouf A et al. (2008) Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell 3(1): 109-18.
Stingl J et al. (2001) Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue.Breast Cancer Res Treat 67(2): 93-109.
EpiCult™-B (Mouse)
Yamaji D et al. (2009) Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A. Genes & Development 23(20): 2382-7.
Stingl J et al. (2001) Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res Treat 67(2): 93-109.
Stingl J et al. (2001) Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res Treat 67(2): 93-109.
Publications on Cancerous Cells
EpiCult™-B (Human)
Kawakubo T et al. (2013) Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer. Carcinogenesis 35(3): 714-26.
D'Uva G et al. (2013) Beta-Catenin/HuR Post-Transcriptional Machinery Governs Cancer Stem Cell Features in Response to Hypoxia. PLoS one 8(11) e80742.
Law JH et al. (2010) Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability. PLoS One 5(9): e12661.
Diehn M et al. (2009) Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458(7239): 780-3.
Lindvall C et al. (2006) The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis. J Biol Chem 281(46): 35081-7.
D'Uva G et al. (2013) Beta-Catenin/HuR Post-Transcriptional Machinery Governs Cancer Stem Cell Features in Response to Hypoxia. PLoS one 8(11) e80742.
Law JH et al. (2010) Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability. PLoS One 5(9): e12661.
Diehn M et al. (2009) Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458(7239): 780-3.
Lindvall C et al. (2006) The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis. J Biol Chem 281(46): 35081-7.
EpiCult™-B (Mouse)
Chen EP et al. (2014) Myeloid COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T lymphocyte function.Carcinogenesis 35(8):1788-97.
Teissedre B et al. (2009) MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors. PLoS ONE 4(2): e4537.
Shimono Y et al. (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138(3): 592-603.
Shafee N et al. (2008) Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors. Cancer Res 68(9): 3243-50.
Teissedre B et al. (2009) MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors. PLoS ONE 4(2): e4537.
Shimono Y et al. (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138(3): 592-603.
Shafee N et al. (2008) Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors. Cancer Res 68(9): 3243-50.
EpiCult™-C (Human)
Zhang L et al. (2013) The identification and characterization of breast cancer CTCs competent for brain metastasis. Sci Transl Med 5(180): 180ra48.
Publications on Non-Mammary Tissue
EpiCult™-B (Human)
Ghosh M et al. (2013) Human Tracheobronchial Basal Cells: Normal Versus Remodeling/Repairing Phenotypes in vivo and in vitro.Am J Respir Cell Mol Biol 49(6): 1127-34.
Matrigel 是 Corning Inc. 的注册商标。
