EasySep™小鼠TIL（CD45）正选试剂盒
产品号 #100-0259_C
mTOR通路抑制剂；抑制mTOR
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总览
Torin 2是一种强效的、选择性的ATP竞争性抑制剂，可抑制mTOR (EC₅₀ = 0.25 nM)， mTOR是细胞生长、存活和自噬的关键调节因子(Liu等人；Petherick等人)。
肿瘤研究
·抑制肺癌、乳腺癌、结直肠癌和宫颈癌细胞系的增殖（Liu等人）。
·阻断mTOR复合物1 （mTORC1）相关的细胞周期进程，诱导肝癌细胞自噬（Wang等人）。
细胞类型
癌细胞及细胞系
研究领域
自噬，癌症
CAS 编号
1223001-51-1
化学式
C₂₄H₁₅F₃N₄O
分子量
432.4 g/mol
纯度
≥98%
通路
mTOR，PI3K/AKT
靶点
mTOR
产品说明书及文档
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Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Torin 2 Catalog #
100-0260, 100-0259 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Torin 2 Catalog #
100-0260, 100-0259 Lot #
All Language
English 相关材料与文献
文献 (3)
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更多信息
| Molecular Weight | 432.4 g/mol |
|---|---|
| Cas Number | 1223001-51-1 |
| Chemical Formula | C₂₄H₁₅F₃N₄O |
| 纯度 | ≥ 98% |
| Target | mTOR |
| Pathway | mTOR, PI3K/AKT |
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