EasySep™小鼠TIL（CD45）正选试剂盒
"Therapeutic T Cell Engineering" Featuring Drs. Carl June and Philipp Rommel
"Therapeutic T Cell Engineering" Featuring Drs. Carl June and Philipp Rommel
Dr. Carl June is the Richard W. Vague Professor in Immunology at the University of Pennsylvania, Director of the Center for Cellular Immunotherapies at the Perelman School of Medicine, and Director of the Parker Institute for Cancer Immunotherapy. Dr. Philipp Rommel is a Postdoctoral Researcher in the June lab. Together, they are interested in lymphocyte biology, with a major translational focus on ex vivo T cell engineering for cancer and HIV cell-based therapies.
Carl June and Philipp Rommel talk about the past, the present and the future of cellular immunotherapy - don't miss this wonderful chat about CAR-T cells and the way forward for solid tumors!
Dr. Brenda Raud, host
Find more episodes at immunologypodcast.com or wherever you get your podcasts.
This Episode's Immunology Roundup:
- Pooled CRISPR Screening Identifies m6A RNA as a Regulator of Macrophage Activation – Scientists identified METTL3-mediated m6A modification in innate immune responses suggesting the m6A machinery could be a target for immunotherapy
- Natural Killer Receptors Fine-Tune T Cells – Researchers identified a role for natural killer cell receptor signaling in regulating self/non-self discrimination by HLA-E–restricted T cells.
- Notch4 Signaling in Viral Infections – Notch4 expression on Treg cells suppressed the induction of amphiregulin and promoted severe lung inflammation in viral infections.
- Synthetic Notch CAR T Cells Targeting Solid Tumors in Mice – Scientists developed synthetic Notch CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma.
沪公网安备31010102008431号