技术资料

产品手册
NaïveCult™ Media System

产品类型：

Cell Culture Media and Supplements

品牌：

NaïveCult
技术窍门
The STEMdiff™ Trilineage Differentiation Kit: Assessing Differentiation to Three Germ Lineages
2:22

视频
How ALDEFLUOR™ ALDH Assay Kit Detects Normal and Cancer Progenitor Cells

发布日期: 12/4/17
3:10

视频
Limitless Potential: Do More with TeSR™

发布日期: 6/14/17
3:23

视频
Passaging Naive PSC Colonies Derived and Maintained in RSeT™

发布日期: 12/14/17
文献

Liu X et al. (NOV 2017) Nature methods 14 11 1055--1062

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming.

Recent reports on the characteristics of naive human pluripotent stem cells (hPSCs) obtained using independent methods differ. Naive hPSCs have been mainly derived by conversion from primed hPSCs or by direct derivation from human embryos rather than by somatic cell reprogramming. To provide an unbiased molecular and functional reference,we derived genetically matched naive hPSCs by direct reprogramming of fibroblasts and by primed-to-naive conversion using different naive conditions (NHSM,RSeT,5iLAF and t2iLGöY). Our results show that hPSCs obtained in these different conditions display a spectrum of naive characteristics. Furthermore,our characterization identifies KLF4 as sufficient for conversion of primed hPSCs into naive t2iLGöY hPSCs,underscoring the role that reprogramming factors can play for the derivation of bona fide naive hPSCs. View Publication
挂图
Building Three-Dimensional Human Brain Organoids Overview of brain organogenesis and the applications of brain organoids in studying the development and maturation of the nervous system
科学海报
BrainPhys™ Neuronal Medium: A Medium That Promotes the Maturation and Synaptic Function of Human Pluripotent Stem Cell (hPSC)-Derived Neurons in Long-Term Cultures

Conference：

CAN 2018,ISSCR 2018
科学海报
Routine Monitoring of Common Genetic Abnormalities in Human Pluripotent Stem Cells Using the hPSC Genetic Analysis Kit

产品类型：

Cell Dyes and Detection Assay Kits

Conference：

ISSCR 2018
技术窍门
STEMdiff™ Neural Induction Medium Versus STEMdiff™ SMADi Neural Induction Kit
技术手册
Reversion and Maintenance of Human Naïve-Like Pluripotent Stem Cells with RSeT™ Medium

产品类型：

Cell Culture Media and Supplements
Interview
Scott Allen, PhD Seeking Metabolic Therapies for an Incurable Neurodegenerative Disease

研究方向：

干细胞生物学，神经科学