搜索结果: 'megacult cytokines cfu'

技术手册
STEMvision™ Automated Colony-Forming Unit (CFU) Assay Reader

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STEMvision™ 人脐带血7-天CFU分析包

STEMvision™ 彩色人脐带血14-天CFU分析包

STEMvision™ 彩色人骨髓14-天CFU分析包

STEMvision™ 彩色人动员外周血14-天CFU分析包

STEMvision™ 小鼠总CFU分析包

STEMvision™ 小鼠髓系CFU分析包

STEMvision™ 小鼠红系CFU分析包

STEMvision™ 小鼠CFU分析包（髓系和红系）
点播课程
Human Hematopoietic CFU Assay Course

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技术手册
Mouse Colony-Forming Unit (CFU) Assays Using MethoCult™

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MethoCult™M3134

MethoCult™M3231

MethoCult™M3234

MethoCult™SF M3236

MethoCult™M3334

MethoCult™GF M3434

MethoCult™SF M3436

MethoCult™GF M3434

MethoCult™GF M3534

MethoCult™M3630
技术窍门
Extending the Life of a CFU Assay
产品手册
Evaluating Hematopoietic Cell Therapy Product Potency Using the CFU Assay

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MethoCult

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技术窍门
Maintaining Humidity in CFU Assays using MethoCult™ Media
35:46

线上讲座
Cytokines and Lineage Choice in Stem Cell Differentiation

发布日期: 05/13/2010
点播课程
Introduction to STEMvision for CFU Assay Scoring Course

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9:06

视频
CFU Assay Setup for Custom Hematopoietic Training Courses

发布日期: 05/25/2017
S. Niyongere et al. (JUL 2018) Leukemia

Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML.

Chronic myelomonocytic leukemia (CMML) is a clinically heterogeneous neoplasm in which JAK2 inhibition has demonstrated reductions in inflammatory cytokines and promising clinical activity. We hypothesize that annotation of inflammatory cytokines may uncover mutation-independent cytokine subsets associated with novel CMML prognostic features. A Luminex cytokine profiling assay was utilized to profile cryopreserved peripheral blood plasma from 215 CMML cases from three academic centers,along with center-specific,age-matched plasma controls. Significant differences were observed between CMML patients and healthy controls in 23 out of 45 cytokines including increased cytokine levels in IL-8,IP-10,IL-1RA,TNF-alpha$,IL-6,MCP-1/CCL2,hepatocyte growth factor (HGF),M-CSF,VEGF,IL-4,and IL-2RA. Cytokine associations were identified with clinical and genetic features,and Euclidian cluster analysis identified three distinct cluster groups associated with important clinical and genetic features in CMML. CMML patients with decreased IL-10 expression had a poor overall survival when compared to CMML patients with elevated expression of IL-10 (P = 0.017),even when adjusted for ASXL1 mutation and other prognostic features. Incorporating IL-10 with the Mayo Molecular Model statistically improved the prognostic ability of the model. These established cytokines,such as IL-10,as prognostically relevant and represent the first comprehensive study exploring the clinical implications of the CMML inflammatory state. View Publication

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技术手册
Human Colony-Forming Unit (CFU) Assays Using MethoCult™

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00215US.4

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造血祖细胞检测标准化培训课程

MethoCult™H4034 Optimum

MethoCult™H4035 Optimum无EPO

MethoCult™H4034 Optimum

MethoCult™ H4034 Optimum启动试剂盒套装

MethoCult™ H4100

MethoCult™H4230

MethoCult™SF H4236

MethoCult™H4330

MethoCult™H4431

MethoCult™H4434经典

MethoCult™H4435富集

MethoCult™ SF H4436

MethoCult™表达

MethoCult™H4434经典

MethoCult™H4435富集

MethoCult™表达

MethoCult™ H4434 Classic启动试剂盒套装

MethoCult™H4531

MethoCult™H4534经典无EPO

MethoCult™H4535富集无EPO

MethoCult™ SF H4536

MethoCult™H4534经典无EPO

MethoCult™ H4535 Enriched，不含EPO

入门套件MethoCult™H4534经典无EPO

含有10% 牛血清白蛋白（BSA）的 Iscove's MDM
实验方案
How to Harvest Cells from CFU Assays

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研究方向：

干细胞生物学，药物发现和毒理检测

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