搜索结果: 'gmp t cell activator'

GloCell™ 可固定活性染料红色 780 用于哺乳动物细胞活/死染色的胺标记荧光染料
GloCell™ 可固定活性染料 Violet 450 用于哺乳动物细胞活/死染色的胺标记荧光染料
GloCell™ 可固定活性染料 Violet 540 用于哺乳动物细胞活/死染色的胺标记荧光染料
GloCell™ 可固定活性染料 Violet 510 用于哺乳动物细胞活/死染色的胺标记荧光染料
GloCell™ 可固定活性染料UV 450 用于哺乳动物细胞活/死染色的胺标记荧光染料
GloCell™ 可固定活性染料红色 710 用于哺乳动物细胞活/死染色的胺标记荧光染料
新品
人iPSC衍生的小胶质细胞 从人诱导多能干细胞系SCTi003-A分化而来的冻存小胶质细胞
人iPSC衍生的神经祖细胞 冻存的人神经祖细胞由人诱导多能干细胞系SCTi003-A分化而来
人iPSC衍生的前脑神经元前体细胞 人诱导多能干细胞系SCTi003-A分化的冻存的前脑神经元前体细胞
Begum AN et al. (JUL 2014) Translational psychiatry 4 January e414

Women with the Alzheimer's risk marker ApoE4 lose A-specific CD4 T cells 10-20 years before men.

Adaptive immunity to self-antigens causes autoimmune disorders,such as multiple sclerosis,psoriasis and type 1 diabetes; paradoxically,T- and B-cell responses to amyloid-$\$(A$\$) reduce Alzheimer's disease (AD)-associated pathology and cognitive impairment in mouse models of the disease. The manipulation of adaptive immunity has been a promising therapeutic approach for the treatment of AD,although vaccine and anti-A$\$ approaches have proven difficult in patients,thus far. CD4(+) T cells have a central role in regulating adaptive immune responses to antigens,and A$\$-specific CD4(+) T cells have been shown to reduce AD pathology in mouse models. As these cells may facilitate endogenous mechanisms that counter AD,an evaluation of their abundance before and during AD could provide important insights. A$\$-CD4see is a new assay developed to quantify A$\$-specific CD4(+) T cells in human blood,using dendritic cells derived from human pluripotent stem cells. In tests of textgreater50 human subjects A$\$-CD4see showed an age-dependent decline of A$\$-specific CD4(+) T cells,which occurs earlier in women than men. In aggregate,men showed a 50% decline in these cells by the age of 70 years,but women reached the same level before the age of 60 years. Notably,women who carried the AD risk marker apolipoproteinE-ɛ4 (ApoE4) showed the earliest decline,with a precipitous drop between 45 and 52 years,when menopause typically begins. A$\$-CD4see requires a standard blood draw and provides a minimally invasive approach for assessing changes in A$\$ that may reveal AD-related changes in physiology by a decade. Furthermore,CD4see probes can be modified to target any peptide,providing a powerful new tool to isolate antigen-specific CD4(+) T cells from human subjects. View Publication

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产品号#：

05850

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产品名：

mTeSR™1

mTeSR™1
DNase I 用于消化DNA
产品手册
qPCR Arrays for Cell Characterization

产品类型：

品牌：

MesenCult

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产品名：

STEMdiff™定型内胚层检测试剂盒

STEMdiff™ 中胚层诱导培养基

STEMdiff™ 中胚层诱导培养基

MesenCult™ MSC 基础培养基（人）

MesenCult™ MSC 刺激补充剂（人）

MesenCult™ 增殖试剂盒（人）

MesenCult™ 脂肪分化试剂盒 (人)

MesenCult™-ACF软骨细胞分化试剂盒

TeSR™-E5

TeSR™-E6

STEMdiff™ 三胚层分化试剂盒

STEMdiff™胰腺祖细胞试剂盒

mTeSR™3D

STEMdiff™ 间充质祖细胞试剂盒

mTeSR™1

mTeSR™1

STEMdiff™ APEL™2 培养基

STEMdiff™ APEL™2 培养基

MesenCult™-hPL 培养基试剂盒

用于hESC/hiPSC维持培养的TeSR™-E8™

人多能干细胞三谱系分化qPCR阵列

qPCR预混试剂盒

qPCR预混试剂盒

Naïve态人多能干细胞 qPCR 阵列

人间充质干细胞 qPCR 阵列分析

不含酚红的mTeSR™1

发布日期: 05/02/2018