搜索结果: 'EasySep Release'

S. Parveen et al. (Jul 2024) iScience 27 8

Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection

Streptococcus pneumoniae is a global priority respiratory pathogen that kills over a million people annually. The pore-forming cytotoxin,pneumolysin (PLY) is a major virulence factor. Here,we found that recombinant PLY as well as wild-type pneumococcal strains,but not the isogenic PLY mutant,upregulated the shedding of extracellular vesicles (EVs) harboring membrane-bound toxin from human THP-1 monocytes. PLY-EVs induced cytotoxicity and hemolysis dose-dependently upon internalization by recipient monocyte-derived dendritic cells. Proteomics analysis revealed that PLY-EVs are selectively enriched in key inflammatory host proteins such as IFI16,NLRC4,PTX3,and MMP9. EVs shed from PLY-challenged or infected cells induced dendritic cell maturation and primed them to infection. In vivo,zebrafish administered with PLY-EVs showed pericardial edema and mortality. Adoptive transfer of bronchoalveolar-lavage-derived EVs from infected mice to healthy recipients induced lung damage and inflammation in a PLY-dependent manner. Our findings identify that host EVs released during infection mediate pneumococcal pathogenesis. Subject areas: Microbiology,Bacteriology,Cell biology View Publication

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15028

15068

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RosetteSep™人单核细胞富集抗体混合物

RosetteSep™人单核细胞富集抗体混合物
新闻
STEMCELL Technologies Releases “Toward Sustainable Science” Report

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发布日期: 10/11/2023
新闻
STEMCELL Technologies Inc. has just released NEW MesenCult™ Proliferation Kit with MesenPure™ (Mouse), a novel cell culture medium to advance research on mouse mesenchymal stem and progenitor cells (MSCs)

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发布日期: 05/09/2014
科学海报
Cell Isolation of Untouched Human Memory CD8+ T Cells

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Conference：

AAI 2012

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科学海报
Cell Enrichment of Mouse Naïve CD4+ T Cells from Spleen

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Conference：

FOCIS 2012

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19765

19765RF

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EasySep™小鼠Naïve CD4+ T细胞分选试剂盒

RoboSep™ 小鼠Naïve CD4+ T细胞分选试剂盒
科学海报
Isolation of Untouched Human Naive and Memory CD8 T Cells

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Conference：

BSI 2011

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19158

19158RF

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科学海报
Positive Selection of Hematopoietic Stem and Progenitor Cells from Adult Mouse Bone Marrow

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Conference：

ASH 2003

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科学海报
Isolation of Highly Purified Mouse CD4+CD25+Foxp3+ Regulatory T Cells in Less

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Conference：

AAI 2014

产品号#：

18782

18782RF

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EasySep™小鼠CD25调节性T细胞正选试剂盒

RoboSep™ 小鼠CD25调节性T细胞正选试剂盒
科学海报
Isolation of Eosinophils Without Ficoll or RBC Lysis

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Conference：

AAI 2007

产品号#：

19256

19256RF

21000

20155

20119

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RoboSep™- S

RoboSep™分选管套装（9个塑料管）

RoboSep™ 吸头组件抛光剂
科学海报
Rapid Isolation of Highly Purified, Functional and Expandable Human Regulatory T Cells

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Conference：

ICRT 2010,ICI 2010

产品号#：

19231

19231RF

19232

19232RF

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EasySep™人CD4+ CD127low CD49d-调节性T细胞富集试剂盒

RoboSep™ CD4+ CD127low CD49d-调节性T细胞富集试剂盒
产品手册
Reliable Antibodies for Your Research

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EasySep

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60100

60100.1

60100AD

60100AD.1

60102

60102FI

60104

60104AD

60104AD.1

60104AZ

60104AZ.1

60104BT

60104BT.1

60104BT.2

60104FI

60104FI.1

60104PE

60104PE.1

60106

60106.1

60106AZ

60106AZ.1

60106BT

60106BT.1

60106FI

60106FI.1

60106PE

60106PE.1

60107

60107.1

601

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抗β-微管蛋白III抗体，克隆AA10

抗β-微管蛋白III抗体，克隆AA10

抗β-微管蛋白III抗体，克隆AA10，Alexa Fluor® 488

抗β-微管蛋白III抗体，clone AA10，Alexa Fluor® 488

抗小鼠TCR Gamma/Delta抗体，clone GL3

抗小鼠TCR Gamma/Delta抗体，clone GL3，Alexa Fluor® 488

抗小鼠TCR Gamma/Delta抗体，clone GL3，APC

抗小鼠TCR Gamma/Delta抗体，clone GL3，APC

抗小鼠TCR Gamma/Delta抗体，clone GL3，Biotin

抗小鼠TCR Gamma/Delta抗体，clone GL3，Biotin

抗小鼠TCR Gamma/Delta抗体，clone GL3，FITC

抗小鼠TCR Gamma/Delta抗体，clone GL3，PE

抗小鼠TCR Gamma/Delta抗体，clone GL3，PE

抗人CD71（转铁蛋白受体）抗体，clone OKT9

抗人CD71（转铁蛋白受体）抗体，clone OKT9

抗人CD71（转铁蛋白受体）抗体，clone OKT9，APC

抗人CD71（转铁蛋白受体）抗体，clone OKT9，APC

抗人CD71（转铁蛋白受体）抗体，clone OKT9，Biotin

抗人CD71（转铁蛋白受体）抗体，clone OKT9，FITC

抗人CD71（转铁蛋白受体）抗体，clone OKT9，FITC

抗人CD71（转铁蛋白受体）抗体，clone OKT9，PE

抗人CD71（转铁蛋白受体）抗体，clone OKT9，PE
产品手册
血细胞重编程的完整流程

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EasySep

产品号#：

00224

00224UK

00224NL

00225

05920

05924

05925

00223NL

产品名：

红系祖细胞重编程试剂盒

CD34+祖细胞重编程试剂盒

发布日期: 03/12/2026