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抗人CD5抗体，clone UCHT2 小鼠Monoclonal IgG1抗体，抗人、恒河猴、食蟹猴CD5
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EasySep™ Release人CD3正选试剂盒 采用可解离磁珠技术的免疫磁珠正选
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Precopio ML et al. (MAR 2003) Journal of immunology (Baltimore,Md. : 1950) 170 5 2590--8

Differential kinetics and specificity of EBV-specific CD4+ and CD8+ T cells during primary infection.

The generation and maintenance of virus-specific CD4(+) T cells in humans are not well understood. We used short in vitro stimulation assays followed by intracellular cytokine staining to characterize the timing,magnitude,and Ag specificity of CD4(+) T cells over the course of primary EBV infection. Lytic and latent protein-specific CD4(+) T cells were readily detected at presentation with acute infectious mononucleosis and declined rapidly thereafter. Responses to BZLF-1,BMLF-1,and Epstein-Barr nuclear Ag-3A were more commonly detected than responses to Epstein-Barr nuclear Ag-1. Concurrent analyses of BZLF-1-specific CD4(+) and CD8(+) T cells revealed differences in the expansion,specificity,and stability of CD4(+) and CD8(+) T cell-mediated responses over time. Peripheral blood EBV load directly correlated with the frequency of EBV-specific CD4(+) T cell responses at presentation and over time,suggesting that EBV-specific CD4(+) T cell responses are Ag-driven. View Publication

产品类型：

产品号#：

15024

15064

产品名：

RosetteSep™人B细胞富集抗体混合物

RosetteSep™人B细胞富集抗体混合物